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Innate Lymphoid Cells: 10 Years On

Citation

  • Verified title: Innate Lymphoid Cells: 10 Years On
  • Publication year: 2018
  • DOI: 10.1016/j.cell.2018.07.017
  • Metadata source: manual-doi-crossref (confidence: high)
  • Original local title: ILC 10 years on

Ingest Mode

  • Mode: focused manual crystallization mode
  • Meaning: this source page has been manually reviewed for final provisional-source cleanup, including source type, tissue context, model boundaries, and whether the source should enter durable synthesis.
  • Required boundary: reusable claims should preserve species, tissue, mediator, disease model, and whether evidence is primary or review-level synthesis.

Source Type

  • review of the first decade of ILC research
  • Evidence profile: field-history review of ILC discovery, subset taxonomy, tissue functions, and disease links.
  • Knowledge note status: source-reviewed evidence note; use according to the boundary notes below.

Evidence Profile

  • Overall confidence: source-specific biological confidence, not processing confidence.
  • Evidence tags: #source/review #species/human #species/mouse #cell/ILC1 #cell/ILC2 #cell/ILC3 #axis/ILC_history #axis/ILC_taxonomy #status/focused_crystallization
  • Primary biological axis: field-history review of ILC discovery, subset taxonomy, tissue functions, and disease links.

Why It Matters Here

This source adds ILC 10 years on to the reference library as trend digest and source spine. It should be used only where that role fits the reader-facing biology narrative.

Key Findings

  • Useful as a field-history anchor for how ILC biology moved from discovery to tissue and disease mechanisms.
  • Supports beginner-facing trend synthesis.
  • Not a source for individual mechanistic claims unless paired with primary papers.

Claim-Level Confidence

  • Medium-high confidence: useful mature review for ILC field history.
  • Low confidence: not a primary mechanistic source.

Methods and Context

  • Source-specific context: review of the first decade of ILC research.
  • Best wiki use: trend digest and source spine.
  • Evidence directness: strongest for the source's own tissue/model; indirect for lung unless lung evidence is present.

Caveats

  • Use for historical synthesis and reading routes.
  • Preserve species, tissue compartment, and source-type labels.
  • Do not use review-level sources as sole support for mechanism-specific causal claims.

Contradiction and Supersession

  • Contradiction status: no direct contradiction resolved in this cleanup pass; use as context alongside primary source anchors.
  • Supersession status: not superseded, but some older reviews are best treated as historical or orientation sources.

Pages Updated From This Source